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  Patronage of the Polish Society of Audiology and Phoniatrics

vol 11. no 3. September 2012  

 Original articles
Wegener’s granulomatosis – accurate and fast diagnostics in ENT Department at District Hospital
Anna Barzyk-Arciszewska, Teresa Tomera-Proksa, Agata Gierlotka

The etiology of Wegener’s granulomatosis has not been completely
explained. The necrotizing granulomatous inflammation
of the respiratory tract seems to play a major role in the development
of the disease. A case of 42-year-old woman treated
at the Department of Otolaryngology for tumour around the
left submandibular gland accompanied by increased body temperature,
sinus inflammation, swelling of both parotid glands
and ulceration of the jaw ridge and palate, and trismus has
been reported. The odontogenic background was excluded.
The patient received large spectrum antibiotics. After USG
examination, the tumour was incised and a large amount of
pus was drained. Computed tomography revealed sinusitis and
re-breaking of sinus wall bones. As the conservative treatment
was ineffective, both maxilliary sinuses were opened from the
Caldwell-Luc approach and material was collected for histological
examination. The results pointed to Wegener’s granuloma.
Corticosteroid therapy was implemented. The c-ANCA antibodies
were assessed an the result was positive, above 200;
the results confirmed the histopathological diagnosis. After the
treatment, there was an improvement in the local and general
condition and the patient was referred to the Rheumatology
Clinic for further treatment.

keywords: ziarniniakowatość Wegenera, c-ANCA, zapalenie naczyń

pages: from 128 to 131

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