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  Patronage of the Polish Society of Audiology and Phoniatrics

vol 10. no 4. December 2011  

 Review articles
Side effects of radiotherapy in patient with head in neck cancer: mechanisms and consequences
Ewa Ziółkowska, Marta Biedka, Wiesława Windorbska

Head and neck squamous cell carcinoma (HNSCC) is the sixth
most common malignancy worldwide and often is associated
with a poor prognosis. Therapeutic decisions are usually
based on clinical pathological parameters like stage of clinical
progression, location of tumour and its histological grading, as
well as patient’s general condition. The role of radiotherapy
in the treatment of head and neck cancer patients is essential
because its effectiveness is comparable to that of surgery, and it
allows to preserve the organ. During radiotherapy, patients with
advanced head and neck cancer very often require aggressive
method of irradiation, such as high total dose and/or concomitant
chemotherapy. The irradiation affects not only the tumour,
but also the normal neighboring tissues. During radiotherapy
of head and neck cancer patients, symptoms of acute mucosal
reaction are major factors in the determination of tolerance
and completeness of treatment.
The aim of this study is to make the clinicians aware of the side
effects of radiotherapy in patients with HNSCC and of the
problems that may arise during their treatment.

keywords: odczyny popromienne, radioterapia, rak głowy i szyi, side effect, radiotherapy, head and neck cancer

pages: from 147 to 153

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