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  Patronage of the Polish Society of Audiology and Phoniatrics




vol 10. no 4. December 2011  
 TABLE OF CONTENT

 Original articles
Localisation and treatment of head and neck region granular cell tumour
Jarosław Markowski, Tatiana Gierek, Jacek Pająk, Ewa Zielińska-Pająk, Małgorzata Witkowska, Katarzyna Pasternak, Piotr Wardas, Karina Podlejska

Introduction. Granular cell tumour, first described in 1929 by
Aleksey Abrikossoff, is a rare tumour developing from Schwann
cells of the peripheral nerve sheath. The Abrikossoff tumour
develops usually between the 4th and 5th decade of life. Head
and neck – especially lateral part of tongue, buccal mucosa, larynx
and oesophagus – is the most common location of these lesions.
The clinical symptoms depend on tumour location and size.
Aim. To assess location and treatment results of granular cell
(Abrikossoff) tumours of the head and neck region.
Material and methods. A retrospective analysis has been
performed of medical documentation of 8 patients treated
between 2000 and 2005 for granular cell tumours. At the
moment of hospitalisation, the age of the patients ranged
from 32 to 60 years. Case histories, surgery protocols, and
documents obtained from the otolaryngology outpatient clinic
were analysed.
Results. Among the study subjects, there were four cases of
tumour located on the tongue, three in the larynx and one in
the oesophagus. Histopathological examination showed that
the Abrikossoff tumour was benign in all cases. Radical tumour
dissection was performed in all patients. Up to now, the followup
has not revealed any signs of the recurrence in the treated
patients.
Conclusions. Abrikossoff tumour, though rare, should be
taken in consideration during differential diagnosis of head and
neck lesions. The prognosis for granular cell tumour is good,
and complete removal of the lesions ensures full recovery in
most cases.

keywords: guz ziarnistokomórkowy, guz Abrikossoffa, region głowy i szyi, granular cell tumor, granular cell myoblastoma,Abrikossoff tumor, head and neck region

pages: from 164 to 170



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