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  Patronage of the Polish Society of Audiology and Phoniatrics

vol 10. no 2. June 2011  

 Original articles
Hearing organ function in children treated for inflammatory connective tissue diseases with non-steroid anti-inflammatory drugs
Piotr Muszyński, Zbigniew Żuber, Magdalena Dutsch-Wicherek, Sebastian Kocoń, Paweł Stręk, Jacek Składzień, Elżbieta Reroń

Introduction. Chronic inflammatory connective tissue diseases
are classified as immunopathies. Transient or permanent hearing
loss resulting from the disease itself or the treatment has been
well documented.
Aim. To evaluate the function of the hearing organ in children
treated with non-steroid anti-inflammatory drugs for chronic
connective tissue diseases.
Materials and methods. The test group included 62 children
hospitalised for connective tissue disease, while the control
group consisted of 40 healthy children. Subjective and objective
examinations and audiometric tests (pure tone, impedance,
speech and transient-evoked otoacousitc emission – TEOAE)
were performed in all participants.
Results. The thresholds of pure tone and speech audiometry
as well as high frequency audiometry results were normal in
all examined children. The stapedial reflex was present, and
the static pressure results were normal in both groups. In the
children with the disease, the values of the gradient and of the
static immitance were lower; the tympanometric curve was of
the As type in as much as 85% of the children. In TEOAE test,
both total and 4 kHz, repeatability was significantly smaller, and
the total response level was significantly lower in the children
with the disease compared to healthy ones and in those treated
for 4 to 6 weeks compared with the children treated for shorter
time (up to 4 weeks).
Conclusions. TEOAE and tympanometry seem to be more
sensitive in assessing hearing organ abnormalities than pure tone,
including high frequency pure tone audiometry, in children treated
for chronic inflammatory diseases of the connective tissue.

keywords: otoemisja, ślimak, choroby tkanki łącznej, otoacoustic emission, cochlear, chronic inflammatory connective tissue diseases

pages: from 81 to 86

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