wersja polska  
Mediton - Publishing House
Start page  Journals  Books  Conferences  News  Mediton  Contact   
   Journals
print this
   Allergy Asthma Immunology - archive  

Allergy Asthma Immunology
     Archive
     Editorial staff
     Editorial board
     For authors
     Subscription
Otorhinolaryngology
Allergology Review



 Search in articles:
  Authority of Polish Society of Allergology




vol 7. no 2. June 2002  
 TABLE OF CONTENT

 Original articles
Nitric oxide and adhesion molecules in exercise-induced bronchoconstriction
Ziemowit Ziętkowski, Anna Bodzenta-Łukaszyk, Marian Tomasik*, Jakub Giergiel**

Klinika Alergologii i Chorób Wewnętrznych AM, ul. Skłodowskiej 24a, 15-276 Białystok
*Zakład Chemii Fizycznej AM w Białymstoku
**AstraZeneca Sp. z o.o.



Aims: The study was aimed to determine the role of nitric oxide and adhesion molecules (sE-selectin and sP-selectin) in the pathogenesis of EIB.
Methods: In total 30 patients were included (16 asthmatics with EIB, 8 asthmatics without EIB and 6 healthy volunteers). In all subjects a non-specific bronchial provocation test with histamine and exercise test using a bicycle ergometer were performed. The study parameters were measured before and then 15 and 60 min. after the exercise test.
Results: In the group of patients with EIB the NO concentration was significantly increased 15 min. after the test as compared to pre-test level, and returned to the norm 60 min. after the test was done. sE-selectin concentration also increased significantly 15 min. after performing the test, and remained unchanged on the 60th min. of observation, whereas sP-selectin concentration was raised 15 min. and returned to normal 60 min. after the exercise test was done. In neither astmatics without EIB nor healthy volunteers group changes of this kind were observed.
Conclusions: The results of the study suggest that the changes in concentrations of NO, sE-selectin and sP-selectin are connected to the mechanisms of exercise-induced bronchoconstriction.
Alergia Astma Immunologia, 2002, 8(2), 110-114


keywords: powysiłkowy skurcz oskrzeli, tlenek azotu, sE?selektyna, sP-selektyna, exercise-induced bronchoconstriction, nitric oxide, sE?selectin, sP-selectin

pages: from 110 to 114



estimated time of download (128 kB)
broadband speed:561282565121024[kbps]
time:279532[sec]


You need to have Adobe Acrobat Reader to view the PDF file. It's free. If you don't have the Adobe Acrobat Reader plugin yet, you can get it HERE.


Start page | Journals | Books | Conferences | News | Mediton | Contact

Copyright © 1996-2020 Mediton Publishing House | All rights reserved.