wersja polska  
Mediton - Publishing House
Start page  Journals  Books  Conferences  News  Mediton  Contact   
print this
   Allergy Asthma Immunology - archive  

Allergy Asthma Immunology
     Editorial staff
     Editorial board
     For authors
Allergology Review

 Search in articles:
  Authority of Polish Society of Allergology

vol 6. no 4. December 2001  

 Original articles
Specific IgE and IgG response to tetanus toxoids after TyT and Td booster
Maria Fiejka, Anna Fordymacka, Paulina Górska, Jerzy Kruszewski, Józef Knap, Janusz ¦lusarczyk

Aluminum hydroxide adsorbed vaccines including diphtheria and tetanus toxoids (DT, Td, T, DTP) frequently cause local adverse reactions. Aluminum stimulates not only the synthesis of IgG but also IgE antibodies.
The aim of this study was to compare the total and specific anti-tetanus IgE antibody response following booster immunization with either aluminium adsorbed (Td) or non-adsorbed (TyT) vaccines.
Two groups of young men aged 19-21 years were examined. One of the groups was vaccinated with Td, and another with TyT vaccine. Antibodies titration was performed in sera obtained before (n=88) and 3 months after (n=84) vaccination with ELISA. Positive sera selected during screening examination were referred as a control.
The study indicated statistically significant (p=0.0011) increase of level of specific anti-tetanus IgE antibodies (0.15±0.3) after Td booster vaccination, in comparison to the pre-vaccination level (0.04±0.1). No statistically significant increase of antibodies after TyT booster vaccination was observed (p>0.05). We have not found any significant differences in the total IgE level between both groups neither before nor after vaccination.
The results indicate that aluminum hydroxide gel adsorbed vaccine caused significant increase of specific anti-tetanus IgE antibodies class after vaccination, when compared with non-adsorbed vaccine.
Alergia Astma Immunologia, 2001, 6(4), 205-208

keywords: immunoglobulina E, szczepienie przypominaj±ce, adiuwant glinowy, szczepionka Td, szczepionka TyT, immunoglobulin E, booster vaccination, aluminium adjuvant, Td vaccine, TyT vaccine

pages: from 205 to 208

estimated time of download (91 kB)
broadband speed:561282565121024[kbps]

You need to have Adobe Acrobat Reader to view the PDF file. It's free. If you don't have the Adobe Acrobat Reader plugin yet, you can get it HERE.

Start page | Journals | Books | Conferences | News | Mediton | Contact

Copyright © 1996-2020 Mediton Publishing House | All rights reserved.