|Andrzej Bożek, Piotr Z. Brewczyński|
Skin prick tests and nasal challenges are - along with the specialist medical history and specific IgE levels - common assays in the diagnostics of HDM allergy. The purpose of the study was to analyse diagnostic value of nasal challenges based on the comparison with skin prick test results. Skin prick tests and nasal challenges with D. pteronyssinus and D. farinae were performed both in 54 patients with suspected HDM allergy and 26 control subjects. Two modes of active, anterior rhinomanometry technique with uni and bilateral allergen spray application were analysed. There was strong correlation between the results at two variants of nasal challenges technique. However, poor correlation of skin prick test and nasal challenge results in patient group was observed, with good accordance of control results. The strong correlation of diagnostic methods mentioned above was found only in patients with enhanced, positive skin prick tests for mites. These data prove limited role of nasal challenges in the diagnostics of HDM allergy.
Alergia Astma Immunologia, 2000, 5(4), 267-273
keywords: roztocz kurzu domowego, punktowe testy skórne, prowokacje donosowe, house dust mites, skin prick tests, nasal challenges
pages: from 267 to 273
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