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  Authority of Polish Society of Allergology

vol 5. no 4. December 2000  

 Original articles
Nasal and paranasal sinus pathology in patients with cystic fibrosis
Dorota Kapiszewska-Dzedzej, Antoni Krzeski

Cystic fibrosis (CF) is the most common genetic lethal disorder of white population. Chronic rhinosinusitis with extensive nasal polyposis is one of the CF manifestations. It is caused by an obstruction of the ostio-meatal complex, which leads to disturbances of ventilation and drainage of the paranasal sinuses. This is the result of longer life time of CF patients.
The aim of the study was to define some characteristic changes revealed by the CT examination of paranasal sinuses and further evaluation of examinations in rhinological patology and diagnosis in patients with cystic fibrosis (CF). The group of 30 CF patients was studied. The control group consisted of 30 patients with chronic rhinosinusitis (CRS). Computed topography (CT) scans were obtained from both groups of patients. CT findings revealed more advanced pathological changes in CF than CRS group. The enhanced inflammatory process observed in CT scans of CF patients resulted in the impairment of frontal and maxillary sinus development, destruction of bone structures in medial projection of the lateral nasal wall.
Alergia Astma Immunologia, 2000, 5(4), 253-262

keywords: mukowiscydoza, błona śluzowa nosa, cytologia, bakteriologia, olfaktometria, tomografia komputerowa zatok, audiometria, rynometria akustyczna, cystic fibrosis, nasal mucosa, cytology, bacteriology, olphactometry, CT, audiometry, acoustic rhinometry

pages: from 253 to 262

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