wersja polska  
Mediton - Publishing House
Start page  Journals  Books  Conferences  News  Mediton  Contact   
print this
   Allergy Asthma Immunology - archive  

Allergy Asthma Immunology
     Editorial staff
     Editorial board
     For authors
Allergology Review

 Search in articles:
  Authority of Polish Society of Allergology

vol 3. no 4. December 1998  

 Original articles
A clinical efficacy of mometasone furoate aqueous nasal spray in patients with perennial allergic rhinitis
Pawe³ Górski, Cezary Pa³czyński, Jolanta Walusiak

Klinika Chorób Zawodowych Instytutu Medycyny Pracy w £odzi, ul. ¶w. Teresy 8, 90-950 £ód¼

Once-daily mometasone furoate nasal spray is a new intranasal glucocorticoid for the treatment of allergic rhinitis. The aim of the study was to evaluate the effectiveness and tolerability of mometasone furoate aqueous nasal spray in comparison to placebo vehicle, in patients with perennial allergic rhinitis. This was a randomised, double - blind, placebo - controlled parallel group study in 105 patients at 5 centres in Poland. Patients allergic to at least one perennial allergen, confirmed by medical history, skin prick test results or presence of allergen - specific IgE in the serum and adequate symptoms were eligible to receive for 8 weeks mometasone furoate, 200µg once daily or placebo vehicle control. Physician evaluation of symptoms was performed after 1, 4 and 8 weeks of treatment and the patients kept daily (morning) symptom diaries. 89 patients were valid for efficacy. Mometasone furoate was significantly (p=0.05) more effective than placebo and well tolerated. Active treated patients demonstrated significant improvement at 1 week of therapy (p<0.005). The results of the study indicate that mometasone furoate aqueous nasal spray adequately controls of perennial allergic rhinitis, offers the advantage of once daily treatment, and is well tolerated.


pages: from 223 to 228

estimated time of download (167 kB)
broadband speed:561282565121024[kbps]

You need to have Adobe Acrobat Reader to view the PDF file. It's free. If you don't have the Adobe Acrobat Reader plugin yet, you can get it HERE.

Start page | Journals | Books | Conferences | News | Mediton | Contact

Copyright © 1996-2020 Mediton Publishing House | All rights reserved.