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  Authority of Polish Society of Allergology

vol 3. no 3. September 1998  

 Original articles
Congenital immunodeficiency syndroms - cases report
Krystyna W±sowska-Królikowska, Aneta Krogulska

I Klinika Chorób Dzieci Instytutu Pediatrii Akademii Medycznej, ul. Sporna 36/50, 91-738 £ód¼

Congenital immunodeficiency syndroms in children and adolescence are relatively rarely recognised, although the symptoms of these diseases appear to be much more frequent. The most important defect in immunological system at this age is the deficiency in immunoglobulins synthesis. The knowledge of symptoms determines the proper diagnosis and treatment. Three cases of children (two boys ages 7 and 12, and one girl age 9) with immunoglobulin deficiencies are presented in the study. They suffered from Bruton's agammaglobulinemia, dysgammaglobulinemia and deficiency in IgA immunoglobulin synthesis, respectively. The clinical symptoms in each child differed, however predominantly the infections in the urinary tract were observed. The diagnosis was made during the hospitalisation due to arthritis, low weight and growth, or pyelonephritis.


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