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Allergology Review

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  Authority of Polish Society of Allergology

vol 3. no 3. September 1998  

 Original articles
Mometasone - a new glucocorticoid in seasonal allergic rhinitis. Clinical efficacy and nasal cytology
Bożena Tarchalska-Kryńska1, Edward Zawisza2, Adam Chustecki3

1)Katedra i Zakład Farmakologii Doświadczalnej i Klinicznej Akademii Medycznej, ul. Krakowskie Przedmieście 26/28, 00-927 Warszawa
2)Poradnia Alergologiczna CSK Akademii Medycznej w Warszawie
3)Klinika Otolaryngologiczna Akademii Medycznej w Wa

Clinical efficacy of 0.05% solution of mometasone, applied nasally in 23 patients with seasonal allergic rhinitis was evaluated in the open trial with saline applied as a control. The influence on the drug on cytology of the nasal mucosa was also evaluated. The nasally applied mometasone significantly alleviated the symptoms of rhinitis and lowered the intake of the supporting drug - loratadine. The drug was well tolerated. The results of cytological evaluation showed a significant reduction in eosinophilia and neutrophilia and the lack of any signs of cytological damage of the nasal epithelium due to the action of mometasone.


pages: from 161 to 166

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