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Allergology Review

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  Authority of Polish Society of Allergology

vol 20. no 1. January 2015  

 Original articles
Allergy to kaki fruit in 72 year-old patient
Natalia Ukleja-Sokołowska, Ewa Gawrońska-Ukleja, Magdalena Żbikowska-Gotz, Zbigniew Bartuzi

There are only few described cases of patients allergic to kaki. Kaki is
the fruit of the Persimmon tree. Kaki allergens identified so far include:
profilin Dio k 4, a protein, 17 kDa (homologous to Bet v 1), food-related
allergen Bet v 6.
A 74 year-old female experienced extensive skin lesions in the form of
polymorphous urticaria on the upper extremities, lower extremities and
neck, and oedema of both eyelids. The symptoms were followed by vomiting
and diarrhea. Symptoms occurred 10 minutes after ingestion of the
second half of a kaki fruit. The first half was consumed on the previous
day without any side effects. Patient never experienced any symptoms
of allergy and the family history of allergic diseases was negative. Symptoms
resolved after steroids i.v. and antihistamine drugs.
Skin prick tests (SPT) were performed with food allergens. The skin prick
test using a standardized kaki allergen was not performed since the
standardized allergen extract was not available. Prick by prick test with
fresh kaki fruit was performed. The patient underwent detailed diagnostic
testing using the immunoblotting method.
Skin prick tests (SPT) with food allergens were negative. The prick by prick
test with fresh kaki fruit was positive (Histamine 6/15mm, kaki 15/15mm).
There was no positive signal obtained in immunoblotting.
The prick by prick test enabled to objectively confirm the source of symptoms
in our patient. Although there was no signal in immunoblotting,
we presume that it did not exclude the presence of specific antibodies
against kaki protein extract and the results may be a consequence of
their low concentrations in the blood serum tested and partial change in
allergen particles due to protein denaturation

keywords: kaki, alergia pokarmowa, reakcja IgE zależna, kaki, food allergy, IgE-dependent reaction

pages: from 53 to 56

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