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  Authority of Polish Society of Allergology

vol 20. no 1. January 2015  

 Review articles
Epidemiology and natural course of allergy to cow's milk protein
Natalia Ukleja-Sokołowska, Zbigniew Bartuzi

Milk protein allergy is a major clinical problem. It is usually the first allergy
noted in infants. Parents often ask about the effect of elimination diet
during pregnancy and breastfeeding on prevention of allergy to milk,
as well as whether and how to cow's milk into the diet of a small child.
In cow's milk there are about 20 proteins. Each one can be a source of
hypersensitivity. Some of them are referred to as major allergens, which
can be found in the fraction of whey or casein. Cow's milk protein allergy
affects up to 2-3% of newborns. In most cases it spontaneously resolves.
Infants affected by non-IgE dependent allergy develop milk tolerance
sooner than those with IgE-mediated allergy.
The high prevalence of allergy to milk and often unusual or severe symptoms
motivate researchers to explain allergy risk factors and find ways to
prevent allergy.
In this report we discuss the epidemiology and natural course of cow's
milk allergy. We also include current opinions on preventing allergy and
ways to modify the natural course of the disease.

keywords: mleko, alergia, anafilaksja, alergeny, immunoterapia, milk, allergy, anaphylaxis, allergen immunotherapy

pages: from 5 to 11

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