|Marta Gruchała-Niedoszytko, Piotr Niedoszytko, Katarzyna Gierat-Haponiuk, Aleksandra Śliwińska, Marek Niedoszytko, Dominika Zielińska, Sylwia Małgorzewicz|
Introduction. Obesity has become one of the pandemics of the modern western societies. The increased body mass has numerous health consequences, including impaired function of the heart and lungs. Cardiopulmonary exercise testing (CPX) can analyze the gas exchange - the major function of cardiovascular and pulmonary system. Obesity may decrease the gas exchange by impairment of heart and/or lung function.
Aim. The aim of the study was to analyze the influence of the obesity and body mass reduction on the oxygen uptake and other parameters analyzed in CPX, and bioimpedance. Additionally, the effectiveness of the body mass reduction protocol was assessed by analysing the CPX results.
Methods. Eight obese patients and eight controls were included into the study. Obese patients were treated by both diet and exercise guided by the results of CPX and bioimpedance for 8 weeks. Five of the obese patients have completed the treatment and achieved mean 8% reduction of the body mass.
Results. Peak oxygen uptake (PK VO2) and anaerobic threshold (AT) were significantly impaired in obese subjects vs lean controls (p=0.0001 and p=0.002, respectively). Respiratory exchange ratio was also lower in obese patients (0.99 vs 1.15 p=0.01). The reduction of body mass improved the analyzed CPX results, but the reduction was not significant.
Conclusions. Obesity has an adverse influence on gas exchange. The analyzed novel protocol of body mass reduction based on CPX results was effective in the group of studied obese patients. The body mass reduction may probably lead to the improvement of gas exchange; however, further studies are needed to confirm the results of this pilot study.
keywords: otyłość, badanie ergospirometryczne, bioimpedancja, obesity, cardiopulmonary exercise testing, bioimpedance
pages: from 42 to 45
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