|Marta Gruchała-Niedoszytko, Marek Niedoszytko, Marta Chełmińska, Aleksandra Górska, Sylwia Małgorzewicz, Ewa Jassem|
Introduction. Food allergy and intolerance present various symptoms, including severe anaphylactic reaction. Patients with mastocytosis are more susceptible to anaphylactic reactions.
Aim. The aim of the study was to analyse the prevalence of food intolerance and food allergy among mastocytosis patients.
Material and methods. The study group comprised 31 patients with mastocytosis diagnosed before 2007. Skin prick tests were performed in patients reporting food allergy and concentrations of sIgE against allergens selected using history-derived information were determined. The 5-year or longer follow-up made it possible to assess the effectiveness of the applied treatment.
Results. Indolent systemic mastocytosis was diagnosed in 17(55%) of patients, 10 (32%) patients suffered from cutaneus mastocytosis and 4 (13%) were diagnosed with monoclonal mast cell activation syndrome. The symptoms of food intolerance were reported by 20 (65%) of patients, while IgE mediated food allergy was diagnosed in 9 (29%) of the subjects.
Conclusions. Food intolerance is common among patients with mastocytosis, while correct diagnosis and treatment are necessary for the improvement of patient’s clinical condition, particularly in cases involving anaphylactic shock reactions
keywords: mastocytoza, alergia pokarmowa, nadwrażliwość pokarmowa,mastocytosis, food allergy, food intolerance
pages: from 231 to 234
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