wersja polska  
Mediton - Publishing House
Start page  Journals  Books  Conferences  News  Mediton  Contact   
   Journals
print this
   Allergy Asthma Immunology - archive  

Allergy Asthma Immunology
     Archive
     Editorial staff
     Editorial board
     For authors
     Subscription
Otorhinolaryngology
Allergology Review



 Search in articles:
  Authority of Polish Society of Allergology




vol 18. no 4. December 2013  
 TABLE OF CONTENT

 Review articles
Isolated angioedema - pathogenesis, diagnosis and principles of treatment
Bernard Panaszek

Angioedema usually is accompanied urticaria, with which it shares the pathogenesis, but in 10% of cases the swelling is not accompanied by hives. It is not clear why, in isolated angioedema, mediators are released only in the deeper layers of the skin and mucous membranes. It seems, however, that in addition to the main mediator, i.e. histamine, also other mediators participate in the formation of an edema. Those mediators are found in abundance in effector cells (mast cells, eosinophils, platelets, endothelial cells), and generated as a result of activation of the coagulation (Hageman factor), the complement (anaphylatoxins), the kinin-forming (bradykinin), and the fibrinolysis (plasmin) systems. Angiotensin converting enzyme inhibitor - (ACEi) - induced angioedema, as well as that associated with the inherited or acquired pathology of the inhibitor of the first constituent of the complement - C1-INH, represent isolated swelling. In contrast to urticaria, isolated angioedema is a transient phenomenon and never occurs in the chronic form. However, until now, the cause of isolated angioedema remains unknown in most cases of diagnosed idiopathic angioedema. Antihistamines are most effective in the treatment of allergic angioedema, but play a lesser role in the treatment of angioedema associated with C1-INH deficiency and ACE-blocking drugs.

keywords: obrzęk naczynioruchowy, C1- INH, ACEi, bradykinina,plazmina, czynniki kontaktu, angioedema, C-1 INH, ACEi, bradykinin, plasmin, contactfactors

pages: from 213 to 220



estimated time of download (778 kB)
broadband speed:561282565121024[kbps]
time:1575025137[sec]


You need to have Adobe Acrobat Reader to view the PDF file. It's free. If you don't have the Adobe Acrobat Reader plugin yet, you can get it HERE.


Start page | Journals | Books | Conferences | News | Mediton | Contact

Copyright © 1996-2020 Mediton Publishing House | All rights reserved.