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  Authority of Polish Society of Allergology

vol 18. no 2. June 2013  

 Review articles
The role of nitric oxide in the inflammed airways
Anna Kłak, Edyta Krzych-Fałta, dr hab. Bolesław Samoliński

Considering its functions in the human body, nitric oxide has been found to be a biologically active compound that plays a key role in both physiology and pathology of the body. Nitric oxide is a marker of nasal mucosa inflammation in patients diagnosed with allergic rhinitis. Measurement of the gas exhaled from both the upper and lower respiratory tract is a non-invasive method. This is important in clinical trials, particularly when assessing the effectiveness of innovative anti-inflammatory drugs. Exhaled nitric oxide measurement test is simple and “patient-friendly,” which is an argument against the use of conventional tests recommended for diagnosing and monitoring of respiratory diseases. The measurement of nitric oxide allows direct monitoring of the inflammatory response in the respiratory tract both in children and adults. Evaluation of nitric oxide in exhaled air provides many important insights into disease processes which take place in the respiratory tract.

keywords: tlenek azotu, drogi oddechowe, stan zapalny, nitric oxide respiratory tract, inflammation

pages: from 91 to 96

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