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  Authority of Polish Society of Allergology

vol 17. no 4. December 2012  

 Review articles
The role of regulatory T cells (Treg) in autoimmunity
Isaura Zaleska, Marta Wawrzyszyn, Anna Chełmońska-Soyta

Although regulatory T cells (Treg) represent only 5-10% of CD4 + cells,
their suppressor activity in the body focused on autoreactive lymphocytes
diminished inflammatory reactions during the course of autoimmune
diseases. Presently, numerous studies indicate that Treg cells may be the
target or therapeutic tool of intervention in autoimmune diseases. The
article presents current information regarding function of Treg and their
participation in multiple sclerosis and rheumatoid arthritis in man and in
corresponding animal models of the diseases.

keywords: komórki T regulatorowe, stwardnienie rozsiane, autoagresja, reumatoidalne zapalenie stawów

pages: from 190 to 196

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