|Ewa Willak-Janc, Paweł Jonkisz|
There are over 8 million dogs in Poland. Allergy to pets accounts for
2.5% of total allergy cases, while allergy to dogs constitutes 8% of the
total pet allergies. About 6% of children with allergic rhinitis and 35%
of the asthmatic children have positive SPTs to dog allergens. Avoiding
of dog allergens is not feasible, since dog antigen is found at concentrations
capable of producing allergic symptoms in all public places.
There are 29 allergic proteins in dog hair, dander, urine, serum and saliva.
Five major dog allergens have been identified: Can f1, Can f2, Can
f3, Can f4, Can f5. Allergens Can f1 and Can f2 are found in dander,
saliva and in skin. Can f3 is found in serum, Can f4 in hair, dander and
skin. Can f5 is found in urine. Can f1 and Can f5 are capable of binding
50-70% of IgE, while Can f2 and Can f3 bind 20-40% of IgE. Considerable
differences have been observed in the quantity of dog allergens
between various breeds, but it does not seem reasonable to regard
any of the breed as hypoallergenic. Effect of influence of dog allergens
and of being an owner of a dog on the development of allergy and
asthma has not been yet clarified. Some authors stress the significance
of constant contact with the animal and of breeding more than one
dog at home. Up to now, it has not been possible to determine the
effect of having a dog at home on development of allergy in children.
keywords: pies, alergia, alergen, astma
pages: from 113 to 117
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