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  Authority of Polish Society of Allergology




vol 17. no 2. June 2012  
 TABLE OF CONTENT

 Original articles
The analysis of epidermal patch tests in contact eczema patients
Milena Wojciechowska, Zbigniew Bartuzi

Introduction. Eczema is a syndrome of polimorphous dermal eruptions
in response to inflammation. Contact eczema is an eczema caused by
contact with environmental agents, usually irritating chemicals or contact
allergens.
Aim of the study. The aim of the study was the analysis of epidermal
patch tests in contact eczema patients.
Material and methods. The study participants included 70 patients
with contact eczema, 41 women and 29 men, aged 18-70. The patients
underwent physical examination and epidermal patch tests with
European Standard Series of allergens using IQ Ultra (Chemotechnique
Diagnostics) chamber application system. The patches were applied
onto patients’ back, in the interscapular region, for 48 hours. After that
time, the patches were removed and first readout was made. The second
readout was after 72 hours from the moment of patch application. The
results were interpreted according to the international patch test results
recording system.
Results. Positive results of patch tests were obtained from 22 (31.4%) patients.
Nickel sulphate was the most frequent sensitizer, with 14 (63.6%)
patients showing positive patch tests to that metal. It was followed, in
the descending order, by potassium dichromide – 8 patients (36.3%), cobalt
chloride – 5 (22.7%), PPD – 3 (13.6%), balsam of Peru – 2 (9.0%), and
fragrance mix I – 2 patients (9.0%). Single patients (4.5%) were allergic
to benzocaine, budesonide, colophony, thiuram mix and cathon CG. Ten
patients (45.4%) were positive to more than 1 hapten. Hands were the
site most often affected by contact eczema, and this was the case in 22
patients (31.4%).
Conclusions. Hands are the sites which are most frequently affected by
contact eczema. Metals, in particular nickel, are the most frequent sensitizers
in patients with contact eczema.
Summary
Introduction. Eczema is a syndrome of polimorphous dermal eruptions
in response to inflammation. Contact eczema is an eczema caused by
contact with environmental agents, usually irritating chemicals or contact
allergens.
Aim of the study. The aim of the study was the analysis of epidermal
patch tests in contact eczema patients.
Material and methods. The study participants included 70 patients
with contact eczema, 41 women and 29 men, aged 18-70. The patients
underwent physical examination and epidermal patch tests with
European Standard Series of allergens using IQ Ultra (Chemotechnique
Diagnostics) chamber application system. The patches were applied
onto patients’ back, in the interscapular region, for 48 hours. After that
time, the patches were removed and first readout was made. The second
readout was after 72 hours from the moment of patch application. The
results were interpreted according to the international patch test results
recording system.
Results. Positive results of patch tests were obtained from 22 (31.4%) patients.
Nickel sulphate was the most frequent sensitizer, with 14 (63.6%)
patients showing positive patch tests to that metal. It was followed, in
the descending order, by potassium dichromide – 8 patients (36.3%), cobalt
chloride – 5 (22.7%), PPD – 3 (13.6%), balsam of Peru – 2 (9.0%), and
fragrance mix I – 2 patients (9.0%). Single patients (4.5%) were allergic
to benzocaine, budesonide, colophony, thiuram mix and cathon CG. Ten
patients (45.4%) were positive to more than 1 hapten. Hands were the
site most often affected by contact eczema, and this was the case in 22
patients (31.4%).
Conclusions. Hands are the sites which are most frequently affected by
contact eczema. Metals, in particular nickel, are the most frequent sensitizers
in patients with contact eczema.

keywords: wyprysk kontaktowy, naskórkowe testy płatkowe, alergia kontaktowa, epidemiologia, contact eczema, epidermal patch tests, contact allergy,epidemiology

pages: from 89 to 96



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