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  Authority of Polish Society of Allergology

vol 16. no 1. March 2011  

 Review articles
Treatment of gastoesophageal reflux improves asthma control (pro)
Joanna Glück

In this article the benefits from the treatment of gastroesophageal reflux
introduced for the patients with asthma have been presented. The
gastroesophageal reflux disease is three times more frequent in the
group of patients with asthma than in general population. The prevalence
is similar in children and adults. Gastroesophageal reflux deteriorates
asthma controls in different ways. It is thought to affect asthma
through the activation of vagal reflexes and/or microaspiration.
Proton pump inhibitors alone or together with prokinetics and H2-receptor
antagonists are used in the treatment of the gastroesophageal
reflux disease. Some surgical procedures have also been introduced.
It has been shown that proton pump inhibitors resulted in decrease
in nocturnal symptoms, asthma exacerbations and improvement of
quality of life. The treatment of the gastroesophageal reflux seems to
be the most profitable in the patients with moderate to severe uncontrolled
asthma with gastroesophageal reflux disease symptoms. Thus
particularly in this group of patients the treatment of the latter should
be taken into consideration.

keywords: choroba refluksowa przełyku, inhibitory pompy protonowej, astma oskrzelowa, gastroesophageal reflux, proton pump inhibitor, bronchial asthma

pages: from 24 to 26

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