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  Authority of Polish Society of Allergology

vol 14. no 4. December 2009  

 Review articles
The ageing of the immune system and allergy in the elderly
Aleksandra Wardzyńska, Marek L. Kowalski

Changing world demographics has resulted in an increase in the
population of the elderly. To provide the best quality of life to people
in this age group, a particular attention needs to be drawn to health
problems of the elderly. Ageing of immune system is associated with
higher mortality from infectious diseases and reduced response to
vaccines. Decline in immune function may be linked to neoplasms
and age-related inflammatory diseases like osteoporosis, type 2 diabetes,
atherosclerosis or Alzheimer’s disease. Epidemiologic studies
have demonstrated that the incidence of atopy and related disorders
decline with age, which may be determined mainly by a decrease of
serum total and antigen-specific IgE.

keywords: starzenie układu odpornościowego, odpowiedź swoista, odpowiedź nieswoista, alergia, astma, ageing of immune system, adaptive immunity, innate immunity, allergy, asthma

pages: from 239 to 247

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