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  Authority of Polish Society of Allergology




vol 13. no 1. March 2008  
 TABLE OF CONTENT

 Original articles
Influence of the acaricide – set on the improvement of mite allergy symptoms
Krzysztof Buczyłko, Barbara Korzycka-Zaborowska, Anna Michalak

Introduction. Early exposure to dust mite allergens may be critical for primary sensitization. Reducing exposure may offer a realistic chance for primary prevention of sensitization and asthma, but it is essential to implement measures that can achieve and maintain the low-allergen environment. However, practical and effective methods to eradicate these allergens from home environments remain elusive. The last few years have seen the introduction of an unprecedented number of new classes of acaricides with innovative modes of action, discovered by traditional screening. Acaricide research has uncovered several unrelated compounds that possess improved properties.
Aim of the study. The aim of this double-blind study was to determine the effectiveness of the acaricide “Alertex-set” in 33 patients with atopic asthma and persistent allergic rhinitis caused by mites.
Material and methods. The symptoms were collected by questionnaire, and the levels of mite guanine were investigated by Acarex-test.
Results. The acaricide used in this study achieved after 4 weeks a significant (p< 0.05) reduction of mite allergen level in the environment (particularly in beds) and a lower level of complaints concerning asthma /rhinitis in the active versus comparable group.
Conclusion. Application of acaricide resulted in a significant reduction of exposure and asthma /rhinitis symptoms in the active versus placebo group.

keywords: roztocze, astma, akarycyd, poprawa, mites, asthma, acaricide, improvement

pages: from 42 to 52



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