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  Authority of Polish Society of Allergology

vol 12. no 2. June 2007  

 Diagnostics and treatment of allergy
Erythema fixum and other less frequent types of fixed drug eruption

The following questions of fixed drug eruption have been discussed: 1/ mechanism of cutaneous memory: serum factor and suppressor/cytotoxic T lymphocytes; 2/ epidemiology in the developed and less developed countries; 3/ genetic predisposition to fixed drug eruption; 4/ clinical picture (affected sites, duration, erythema, bullous eruptions, hyperpigmentad and nonpigmented lesions, constitutional symptoms); 5/ FDE-triggering drugs: barbiturates, antibiotics, aspirin and other non-steroidal anti-inflammatory drugs and some other drugs; 6/ cross reactivity of some drugs in fixed drug eruptions; 7/ fixed drug eruption due only to combination of two drugs; 8/ diagnostic methods, especially oral and topical provocation.

keywords: trwałe wykwity polekowe, rumień trwały, przebarwienia, antybiotyki, niesteroidowe leki przeciwzapalne, fixed drug eruption, erythema fixum, hyperpigmentations, antibiotics, non-steroidal anti-inflammatory drugs

pages: from 67 to 72

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