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Allergology Review

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  Authority of Polish Society of Allergology

vol 12. no 1. March 2007  

 Original articles
Total and specific serum IgE levels in the elderly allergic patients

Introduction. Late onset of allergy in people after 65 is more often nowadays. In this group of patients proper and effective methods of diagnosis are required.
Aim of the study. Assess total and specific IgE serum concentrations in the elderly patients with suspected allergy compared to young allergic patients.
Material and methods. 1033 elderly allergic, 868 young allergic patients and 953 elderly healthy subjects were included into the study. Total and specific serum IgE were measured in all patients by immunoenzyme assay.
Results. Significantly lower mean total and specific IgE levels in response to grass, birch, mite, Alternaria and cat were observed in the group of the elderly allergic patients compared to the allergic young subjects. Significant negative correlation between the age of the allergic patients and total serum IgE level was proved. The mean value of total serum IgE in healthy patients after 65 yrs was 79.2 kU/L and was significantly lower than in the allergic patients.
Conclusions. In allergic subjects total serum IgE level correlates with patients age and total and specific IgE serum concentrations are lower in elderly patients above 65 yrs than in the young ones.

keywords: IgE, wiek podeszły, alergia, IgE, elderly, allergy

pages: from 46 to 50

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