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  Authority of Polish Society of Allergology

vol 12. no 1. March 2007  

 Postgraduate education
Diagnosis of hymenoptera allergy

Hymenoptera venom allergy is the most frequent cause of anaphylaxis in humans. Its diagnosis involves deciding whether the post-sting reaction is allergic or non-allergic, classification of the reaction according to Mueller's scale (local, systemic I-IVo), identification of the insect perpetrator and determination of the reaction's pathomechanism (IgE dependent, IgE non-dependent, non-immunological). The first two tasks are realized through anamnesis which helps to reduce the number of patients requiring further diagnostic procedures to those manifesting severe systemic reactions (IIIo and IVo). In order to determine the mechanism of the sting reaction, "in vivo" (prick and ic skin tests) and "in vitro" (serological and cellular) tests are required that are decisive for qualifying or disqualifying patients for venom immunotherapy.

keywords: alergia na jad owadów, anafilaksja na jady owadów, hymenoptera allergy, anaphylaxis reaction to insect venom

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